The drug can be considered as chemical tools to make changes in the system with some precision, depending on where the drugs are effective. Nicotine is not a drug used therapeutically, except for smoking cessation. When introduced into the body through the products, it has wide-ranging effects on the autonomic system. Nicotine carries the risk of heart disease and blood vessels due to the wide influences. Drug stimulates both homogeneous and heterogeneous nodes in the fiber clamp before node. For most organs of the body in the body, and the introduction of competition from two fibers next to the contract essentially cancel each other out. However, the system of the heart and blood vessels, and the results were different. Because there is essentially no effect on the parasympathetic blood for the entire body pressure, and increased contribution sympathy of nicotine, which causes an increase in blood pressure. Also, the impact on his autonomous system on the heart are not the same as for other systems. Other devices have a smooth muscle or glandular tissue that are activated or discouraged by the Independent System.